Protein Electrophoresis
Protein electrophoresis is a diagnostic technique used to evaluate protein levels in dogs by separating proteins based on their electrical charge and molecular weight. This test is especially useful in identifying and characterizing various protein fractions, including albumin and globulins (alpha, beta, and gamma), which helps to detect abnormalities associated with neoplastic, inflammatory and immune-mediated diseases.
Test name
Protein Electrophoresis
Test Code
1018
Section
Cancer Diagnostics
Species
Canine and Feline
Specimen
2 ml Serum
Collection Guidelines
- Collect an adequate amount of blood in a plain red-top tube or serum separator tube (yellow-top tube). Allow it to clot at room temperature for 30 to 60 minutes before separation.
- Centrifuge to separate the serum. Transfer the clear serum into a new, leak-proof plain red-top tube and label it as “serum.”
- Excessively hemolyzed samples are not suitable for this test.
- Unspun samples will not be accepted.
- Refrigerate sample at 4oC until shipment.
Turnaround time
14-21 days
Packing Instructions
Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label. Ensure the submittal form is completed with the animal’s information and relevant medical history.
References
- Tappin, S.W., et al. “Protein Electrophoresis in Veterinary Medicine: Interpretation and Clinical Application.” Journal of Veterinary Internal Medicine, 2021.
- Willard, M.D., & Twedt, D.C. “Diagnostic Use of Serum Protein Electrophoresis in Dogs with Chronic Inflammatory and Neoplastic Disorders.” Veterinary Pathology, 2022.
- Day, M.J., et al. “Applications of Serum Protein Electrophoresis in Veterinary Diagnosis.” Journal of Small Animal Practice, 2023.
